The COVID-19 pandemic has sent students and teachers home, and during the last several months they have learned to study and teach online. Hence, e-learning has become a hot issue and provides the theme for this book. The aim of this book is to link theoretical approaches with practical experiences and inspire teachers, students, and researchers in the field of e-learning in higher education. By reading this book, teachers in higher education may learn lessons from colleagues’ experience that may enable them to dare trying out new ways of e-learning. This book includes contributions from four continents -- the USA, South America, Africa and Europe -- and the authors detail technical considerations as well as provide the different perspectives on e-learning of faculty, teachers, and students.