Advances in Genetics Research presents original research results on the leading edge of genetics discovery. Each article has been carefully selected in an attempt to present substantial research results across a broad spectrum. In this continuing series compilation, the authors present and discuss varied topical data such as gene therapy for hepatocyte growth factor supplementation in the rescue of incurable organ diseases; targeting bacteriocin genes in lactic acid bacteria; nanomedicine based strategies for RNA therapeutics; y-H2AX formation and chromatin structure and targeting notch genes for novel therapy in pancreatic cancer.