This book presents current research in the study of analgesics. Topics discussed include the role of intravenous NSAIDs in the multimodal management of postoperative pain; analgesic use in the management of painful diabetic neuropathy; modulation of the development of morphine antinociceptive tolerance by endoplasmic reticulum chaperones; analgesics effect on traditional medicine through their modulation on tetrodotoxin-resistant sodium channel and transient potential vanilloid receptor 1 and the efficacy of neurotropin in chronic fatigue syndrome.