This continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed include cosmeceuticals; prostaglandins and neural function; expression and involvement of cytokines, chemokines and adhesion molecules in rheumatoid vasculitis; understanding soybean rust interaction with soybean using biotechnology; diversity and evolution of fungal phytopathogens associated with snow; development of antidiabetic herbal formulations; the action mechanism, biological effect and clinical significance in improving peripheral arterial blood flow of prostaglandin E1; molecular basis of hemibiotrophy in the lentil anthracnose pathogen colletotrichum truncatum; detection of gaze atypical patterns in Austism Spectrum Disorders; and game-based learning and serious game utilization for people with ADHD.