In this book, the authors present current research in the study of new technologies, applications and impacts on the environment and industrial processes relating to automation systems in the 21st century. Topics discussed in this compilation include automated native sample preparation for proteome analysis; modern automation in warehousing by using shuttle based technology; flow methodologies from the point of view of green analytical chemistry; cross-coupling digital control of multi-independent servo-drives; and challenges on the way to automatic network intrusion detection.