We are constantly exposed to a plethora of different chemicals, the majority of which are mostly uncharacterised with respect to their biological properties. This book provides an in depth overview on known neurotoxicity mechanisms for a group of industrial chemicals known as polybrominated diphenyl ethers (PBDEs). Polybrominated diphenyl ethers (PBDEs) are ubiquitous environmental toxicants that have been found world-wide in a variety of biotas. This book reports and discusses the interesting and salient work published on the known and potential mechanisms behind the developmental neurotoxicity of PBDEs in the foremost used model organisms, mouse and rat.