Hypertension is the most common chronic disease in developed societies, affecting >25% of adults. Chapter One analyses the current evidence about exercise and hypertension. In Chapter Two, a mesh free numerical scheme was proposed, with the aim to resolve the Navier-Stokes equations for the blood flow through the aorta artery with aneurysm disease. Thoracoabdominal aortic aneurysm repairs are considered one of the most complex procedures known to surgeons. Chapter Three presents a review of thoracoabdominal aortic aneurysm repairs in order to provide the fundamental knowledge and updated techniques for the cardiac and vascular surgery team. In Chapter Four, the authors describe coronary hypersensitivity angitis and acute coronary hypersensitivity syndrome (ACHS) in terms of pathogenesis, clinical presentation, diagnostic work flow, treatment and prevention. Sinus bradycardia is a common clinical or electrocardiographic finding in both healthy and severely ill patients, reflecting the broad spectrum of pathophysiological substrate and clinical relevance of this disorder. Chapter Five provides a comprehensive overview concerning diagnosis, management and prognosis. Chapter Six discusses how patients who were diagnosed with cirrhosis had higher concentrations of NT pro-BNP if they had left ventricular diastolic dysfunction. The authors discuss how NT pro-BNP might be a useful early marker of cardiomyopathy in patients with cirrhosis. Finally, Chapter Seven helps the reader to understand a patient’s experience of undergoing a CATH procedure, particularly the psychological aspect of the procedure and the lived experience of patients undergoing a CATH.