In this yearbook for 2012 we present you with the latest research on pain management. We start our with experience from Hong Kong on palliative care and the four year training program and then further along the pages of this yearbook you will find information about pain, psychological symptoms and prescription drug misuse in HIV, oxygen therapy in patients with advanced lung disease, pain beliefs and pain-related profiles of older persons living in nursing homes, happiness among community-dwelling older persons, fibromyalgia in women, chronic headache, pain management programs, and the role of radiotherapy for the management of painful bone metastases. It is our hope that you as the reader will find the information of interest and useful.