This book offers a system based approach covering a broad range of topics in general medicine for dental practice. The book includes chapters on history taking and patient interview, general physical examination, system specific examination, common health related complaints, systemic infections, and diseases of the gastrointestinal, cardiovascular, respiratory, neurological, immunological, renal, endocrinal, dermatological and musculoskeletal systems. Nutritional disorders, psychiatric disorders, the female patient with menstrual, menopause and pregnancy related disorders, dental management of patients taking medications for systemic conditions and medical emergencies in dental practice have also been discussed in some detail. The book is written in a lucid and user friendly style. Systemic diseases are discussed starting with definitions or descriptions of the diseases followed by their causes, symptoms and signs including oral manifestations, diagnostic aids and principles of management. Dental management considerations are also dealt with where applicable. Target readership of this book includes undergraduate and post graduate dental students, practicing dentists and those preparing for licensing, membership, and fellowship and board examinations. The book should also be useful for faculty members in structuring their lectures, short answer questions, multiple choice questions and viva voce examination questions. This book can serve as a quick reference source in the outpatient clinics and hospital wards and for revision purposes prior to examinations.