Chapter 1 focuses on taxonomic, cultivation and the pharmacological and other uses of Origanum species. In Chapter 2, Origanum‘s role in synthesising the metal nanoparticles such as titanium dioxide,palladium, silver, gold, palladium nanoparticles supported on magnetic graphene oxide has been discussed in detail. Hence, researchers are using Origanum as a precursor in plant-mediated synthesis. In the last chapter, the authors discuss Origanum, the Turkish spice, which has a history dated back to centuries. This herb has found wide applications due to the presence of primary and secondary metabolites.