Methamphetamine abuse is a significant problem in the United States. It is used by nearly 530,000 Americans ages 12 and older, but the effects are devastating to family and friends of addicts. In this book, the authors present topical research on the abuse, health effects and treatment options of methamphetamine. Some of the topics discussed include the effects of methamphetamine exposure during brain development on cognition and markers of cognitive function; what rodent activity can tell us about methamphetamine abuse; sigma receptors as a potential target for methamphetamine abuse and dependence and methods for confirmatory analysis of methamphetamine in biological samples.