Primary Ciliary Dyskinesia is a rare disease with a prevalence of 1:20.000 births (ORPHA244). Understanding Dyskinesia aims to give an overview of what primary ciliary dyskinesia is, the differences in patients' clinical manifestations throughout their lives, its genetics, and diagnostic tests available for this disease. The authors present a systematic review of tardive dyskinesia, covering the clinical manifestations, epidemiology, etiology, and an update on the therapeutic approach. In addition, the acute effects of physical activity and exercise adaptation on different types of dyskinesia are assessed.