This practical handbook of pediatric critical care is written for all clinicians who care for children with acute illness. Specifically, chapters are written to provide helpful insights to all levels of pediatric providers including PICU nurses, Advanced Practice Nurses based in the PICU, medical students, pediatric residents, residents from other disciplines who rotate through PICU, hospitalists who may need to stabilize children prior to transfer to the PICU, and emergency physicians who may want to refer patients to the PICU. In addition to covering PICU-specific topics such as mechanical ventilation and procedural sedation, this handbook also includes guidance in the initial resuscitation, management and stabilization of critically ill children. Management of life-threatening situations that are specifically included in this book include respiratory failure, cardiovascular failure, electrolyte derangements, diabetic ketoacidosis, burn injuries, status epilepticus, status asthmaticus, toxic ingestions, and sepsis, among many others. This easy-to-read handbook covers basic and fundamental concepts of pediatric critical care medicine and makes for easy reading when on call, at the bedside, or when evaluating a child who may need critical care services. At the same time, Pediatric Critical Care: A Primer for All Clinicians provides a quick and practical reference with high-yield information for the clinician who finds themselves in an emergency situation in need of immediate guidance for stabilization and management. We hope that you enjoy this compendium and most of all our intent is that you will find it useful and practical in the everyday care that is provided to critically ill neonates, infants, children and adolescents with the wide array of critical illnesses that you encounter every single day.