This continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed include the role of asymmetrical organisation of the nervous system in blood pressure control; the blood-brain barrier in health and disease; molecular complexes of antigen and adjuvant in vaccine development; oral hygiene behaviour in adolescents; abdominal aortic infections and hypnoanalysis for skin disorders.