Intellectual disability occurs with a frequency of 1-3% within the general population. This impairment is frequently associated with additional features like multiple congenital anomalies and facial dysmorphisms. This book presents current research in the management, causes and social perceptions of mental retardation. Topics include chromosomal regions with a high diagnostic impact in mental retardation syndromes; psychosocial and psychopharmacological treatment of comorbid aggression in paediatric mental retardation; caring for children with Williams and Smith-Magenis syndromes; and cognitive skills enhancement in mental retardation.