This book examines and determine the effects of loads on physical structures and their components. This technology substantially incorporates a number of science and engineering fields, such as material science, applied mechanics, chemistry, mechanical and engineering design, computational simulation, earthquake engineering, architecture, and pharmacological, etc. Therefore, investigation on the research and development of structural analysis and modelling is of great significance and will have profound potential impact on the above areas. This book examines the recent studies and achievements made in the structural analysis and modelling. In the book, Chapters 1 to 5 demonstrate the structural properties and molecular dynamics of chemical materials that are extensively applied in chemistry, chemical engineering, and pharmaceutical. Chapters 6 to 10 present analytical and numerical modelling and analysis of engineering materials and structures, such as honeycomb structures with cellular materials, elastic/plastic discs, stiffened plates, and civil aircraft. Chapters 11 and 12 discuss the structural behaviour and seismic response of engineering architectures through a thorough seismic analysis. The Chapters in this book testify to the vitality of structural analysis and modelling and illustrate the considerable potential for use of these techniques in the future. The book is intended to serve as a reference for researchers and engineers, as well as graduate students.