A common approach for solving simulation-driven engineering problems is by using metamodel-assisted optimization algorithms, namely, in which a metamodel approximates the computationally expensive simulation and provides predicted values at a lower computational cost. Such algorithms typically generate an initial sample of solutions which are then used to train a preliminary metamodel and to initiate an optimization process. One approach for generating the initial sample is with the design of experiment methods which are statistically oriented, while the more recent search-driven sampling approach invokes a computational intelligence optimizer such as an evolutionary algorithm, and then uses the vectors it generated as the initial sample. This book discusses research and new developments on evolutionary computation.