This book provides research on the components, functions and diseases of the lymphatic system. Chapter One reviews the role of lymphatic drainage of cerebrospinal fluid from the brain. In particular, the authors review the current hypotheses on the possible drainage of lymphatic fluid from the brain. Chapter Two expose the actual refinements of the surgical technique for the pedicled and free greater omentum flap, facing the treatment lymphedema. Chapter Three summarises the recent development of the molecular mechanisms of tumor lymphangiogenesis, especially the role of bone marrow-derived cells and the growth factors implicated in this process. Chapter Four reviews molecular mechanisms related to the activation of tumor lymphangiogenesis and their clinical implications.