The field of gastrointestinal biology has been transformed by an explosion of knowledge for gastrointestinal motility, absorption, and secretion. The chapters in this book summarise the methods of molecular biology and the cell biology of gut enzymes, secreting cells and cells that respond to these enzymes. This book is a valuable reference for students, researchers and faculties of gastrointestinal motility, absorption and secretion. No other single source covers this field so comprehensively. It contains a considerable amount of detail on subjects such as gut hormones, gut malabsorption, alcohol toxicity on the stomach and methods used in physiologic study of the digestive tract. Disease conditions are discussed only to the extent that they illustrate physiologic mechanisms. It is difficult for such a comprehensive work to remain up to date for very long, considering how rapidly our knowledge of life sciences expands. This book, a comprehensive treatise on the causes, diagnosis, and management of gastrointestinal-motility disorders, consists of eighteen chapters with extensive references contained in slightly fewer than 300 pages. It achieves its goal through generally lucid writing and the overlap of information from chapter to chapter commonly observed in multi-authored works. Therefore, the reader is best advised to go through this book in a relaxed manner; this will allow them to finish it in a relatively short amount of time and appreciate the field of gastrointestinal motility, particularly current practices and research methods for solving its many riddles. All the chapters are clearly written, but the target audience seems to vary from medical students to practicing gastroenterologists. Despite these drawbacks, gastroenterologists, surgeons, and basic scientists wishing to bring their general knowledge of clinical motility disorders up to date will find this book useful.
Dr. Senthilkumar Rajagopal secured PhD in Biochemistry from Annamalai University, INDIA. He did his three Post-doctoral researches in Anesthesiology in University of Virginia, Charlottesville, Virginia, followed by Department of Cancer Immunology & AIDS, Dana Farber Cancer Institute, Harvard University, Boston, Massachusetts and, Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, USA. He is currently working as a Scientist at Nizam College, Osmania University, Hyderabad, INDIA. Dr. Senthilkumar is a recipient of Rameshwardasji Birla Smarak Kosh Endowment award from Mumbai Medical Trust, Mumbai, INDIA and Ramalingaswami Re-entry Fellowship from Department of Biotechnology, Ministry of Science and Technology, Government of India. Dr. Senthilkumar has more than 10 years of research experiences in various fields such as Alcoholic hepatotoxicity, Voltage gated calcium channels, protein kinase C phosphorylation, ADAM family, Smooth muscle physiology, G-protein coupled receptor signaling pathways, Neurotransmitters transporters to Central Nervous system. He has published nearly 40 research articles in various peer-reviewed international journals, 5 book chapters, 7 abstracts, 37 conferences proceedings/abstracts and attended 30 various workshops/seminars in India, Canada and USA. He is on the editorial/reviewer board in 20 peer-reviewed international journals such as Frontiers in Cellular Neuroscience, American Journal of Biochemistr