The Complutenser Polyglotte was a monument not only to its editors, but also to the culture and time in which it was created. Séamus O’Connell’s study provides a focused view of Spanish science and early modern intellectual culture, showing how the Hellenists of Alcalá edited and compiled their manuscripts. By placing the Greek text of the Old Testament of the Complutenser Polyglot in the historical framework of the Greek text editions of the Old Testament, he is embarking on a new research direction that provides valuable impulses for further research in this area.