This book investigates the emergence of the modern human sciences and their impact on literature, art and other media in the 18th and the 19th centuries. Up until the 1830s, science and culture were part of a joint endeavour to discover and explore the secret of life. The question 'What is life?' unites science and the arts during the Ages of Enlightenment and Romanticism, and at the end of the Romantic period, a shift of focus from the human as an organic whole to the specialized disciplines signals the dawning of modernity. The emphasis of the edited collection is threefold: the first part sheds light on the human in art and science in the Age of Enlightenment, the second part is concerned with the transitions taking place at the turn of the 19th century. The chapters forming the third part investigate the impact of different media on the concept of the human in science, literature and film.