This continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed in this compilation include the cell cycle alteration in down syndrome; TLR agonists as immune adjuvants; heart rate variability in eating disorders; current trends in glaucoma; pharmacological aspects of borates; phage display technology and the quantitative determination of oxytocin.